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Dr. Tim Zacharewski, professor and researcher for the Institute of Integrative Toxicology at Michigan State University, will make a presentation titled "Aryl Hydrocarbon Receptor-Mediated Metabolic Reprograming in 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-Induced Hepatotoxicity"

In this presentation, the dose-dependent effects of TCDD on differential gene expression leading to metabolic reprogramming and the production of highly reactive toxic intermediates following disruption of hepatic circadian regulation and lobular zonation will be discussed.

This talk is hosted by the biological sciences department and the Center for Biomedical Research.

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